Senior Scientist - Immunology
AstraZeneca

AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. The vision of AstraZeneca Early Respiratory & Immunology is centred on delivering life-changing products that advance world health and help fight and cure disease. Here, you'll have the opportunity to make a difference in people's lives every day.

Introduction to role:
Join our Bioscience Asthma & Skin Immunity research group in Gaithersburg, US as a Senior Scientist. This role is perfect for a motivated researcher with experience in lung/skin immunology and primary immune cells. Your enthusiasm for innovative scientific research will drive the discovery and development of novel therapeutics.

Accountabilities:
As a lab-based researcher, you will have the opportunity to shape the direction of our work. You will focus on characterizing novel biology pathways, collaborate with scientists from various teams, mentor junior scientists, and publish your work in high impact journals and international conferences. Your work will involve human in vitro systems and working with primary and disease tissue-derived cells.

Essential Skills/Experience:

• A Ph.D. and a minimum 3 years of Postdoc and/or Biotech/Pharma experience in Immunology with major focus on lung or skin. M.Sc. and a minimum of 10 years of Biotech/Pharma experience will also be considered.
  

• In vitro culture, differentiation and functional assays using human primary cells
  

• Processing of human tissue samples (e.g. skin biopsy processing, epidermal and dermal separation, peripheral blood mononuclear cell isolation)
  

• Functional in vitro assays (co-culture experiments, MSD multiplex cytokines, screening of compounds)
  

• Strong hands-on skills in basic biochemical and molecular techniques including cell culture, quantification of mRNA (qPCR) and protein expression; ELISA, Western blot, Immunohistochemistry and flow cytometry.
  

• Highly organized and self-motivated, with the ability to work independently as well as collaboratively within a team to conduct a high-level research project.
  

• Strong written and oral communication skills and the ability to critically analyze data sets.
  

• Demonstrated ability to run collaborative efforts and utilize external resources to find the most effective solutions to deliver high-quality science, translatable to human disease.
  

• Excellent publication record (project is expected to yield publication of scientific results in peer-reviewed journals) and the ability to apply current scientific literature to projects.
  

Desirable Skills/Experience:

• Experience with primary human cell isolation, culture and functional assays
  

• Effective contributing to collaborative projects involving cross-disciplinary and global teams.
  

• Experience with mentoring students at the undergraduate and Ph.D. level.
  

• •Scientific creativity and ability to drive own research ideas to a successful conclusion, demonstrated by strong publication record or project progression
  

• Drive for constant personal development and increasing skill base.
  

Why AstraZeneca?

At AstraZeneca, we seize opportunities for change, recognizing their potential to drive significant advancements. Our mission to deliver life-changing medicines is fueled by ambition-finding those moments that can lead to extraordinary outcomes. Join us on our journey to redefine what a biopharmaceutical company can be. We are pioneering innovative methods and bringing together diverse teams to achieve our goals.

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

Where can I find out more?

Our social media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long-term incentive. We have a generous paid time off program and a comprehensive benefits package. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

The annual base pay (or hourly rate of compensation) for this position ranges from $105,875.20 - $158,812.80 USD, either as annual base pay or as the hourly rate (annual base pay divided by 2080 hours)]. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

---